Research Fellow in Molecular Pharmacology (fixed-term) In Nottingham
The role will provide support to a new MRC programme grant that aims to determine how adenosine receptor subtypes: (i) form stable or transient oligomeric complexes in different cell types at endogenous levels of receptor expression and, (ii) how their expression levels, ligand-binding characteristics, and propensity to form these complexes are altered by drugs, local inflammatory mediators and hypoxia.
The role holder will undertake fluorescence correlation spectroscopy, advanced imaging studies and use nanobodies and NanoBRET/nanobody approaches to study adenosine receptor function in different cell types including human macrophages, stem-cell derived cardiomyocytes and fibroblasts.
Candidates should have a PhD or equivalent in pharmacology or a related discipline, along with a proven track record of molecular pharmacology research and experience with the study of G protein-coupled receptors in cell systems.
The successful candidate will join a vibrant cell signalling research group within the Centre of Membrane Proteins and Receptors in Nottingham.
This full-time fixed-term post is available from 01 April 2022 until 31 March 2026. Job share arrangements may be considered.
Informal enquiries may be addressed to Professor Stephen Hill: steve.hill@nottingham.ac.uk
Please note that applications sent directly to this Email address will not be accepted.
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